A nice thing about BeetleGone & GrubGone (Btg) is that they have been specifically developed for Japanese beetles. There are a number of strains of Bt, but they have different target organisms. Bt aizawai is particularly effective against grape berry moths and wax moth larvae. Bt kurtaski is good against lepidopterans (moths and butterflies), so is used effectively on cabbage family plants (kale, broccoli, etc.). Some Btk strains can actually help parasitic wasps. Bt israelensis is good against dipterans (mosquitoes, gnats, flies) but do not affect other species, so would be no good against Japanese and other beetles. When using any broad spectrum insecticide, such as soap, pyrethrin or neem, you have to be really careful about harming beneficial insects. I had to rescue and wash off a couple of praying mantises this year when trying to reduce the numbers of JB on the grapes and squash bugs & cucumber beetles on the squashes.