The last time I used an enzyme it made a 1,000 pounds of Zin a mess to press / clear and the resulting wine was overly tannic. I could however see the use of the enzyme in certain cases where it would be beneficial. I am not against enzymes, but I only use it to solve a deficiency that I see in the fruit to start with.
The mess you are referring to might have been fairly recent since I remember reading about it. If I remember correctly it was with a bladder press. When you make 1000 lbs I make 100 lbs so my mess is only 1/10 of yours, perhaps I'm just a glutten for punishment.