It would help to know what type of wine you like to drink.
Frontenac - red grape - very hardy and will grow well.
In a good year this can make a nice oaked dry red wine. The grape can be higher in acid so acid adjustments and/or sweetening may be needed. Many wineries make a slightly sweet red or a sweeter rose style wine from it.
Frontenac Gris - a delightful "pink/grey" grape that makes a wine ranging from almost a rose color to straw white. For us this grape expressed tropical notes of pineapple and mango. We make a sweeter white wine from it. It also has the same hardiness and high acid as the red frontenac.
St. Croix - a cold hardy red grape. Personally not my favorite, but others like it a lot for a sweet wine. It can come accross vegetative in it's flavors due, I think, to the riparia (wild grape) in its lineage. For my tastes, I would pass on it.
LaCrescent - one of my favorite white wine grapes. It has wonderful fruit and floral notes that makes a nice off dry or sweeter white wine similar to maybe gewürztraminer. The aromas are incredible.
Marquette - This can make a great dry oak aged red. It should ripen well to bring the acids into an acceptable range. It has Pinot Noir as one if its grandparents but has a bit more fruit. It expresses nice red cherry flavors. It is light on tannins so makes for an easy drinking red. It benefits from barrel aging. In some years if the acids are still high it can be sweetened to balance. It does tend to have a little bit earlier bud break than I would like thus it is susceptible to spring frost damage. Up here in zone 4/3 die back on marquette is frequent. But it is one of my favorites for flavor, so that could be worth it.
Someone mentioned
Petite Pearl. This makes a very nice wine. The vines are a little slower to establish than others but once growing, seem to do well. This was developed by the private breeder Tom Plocher. He has also released two newer red grape varieties that look even better. They are
Crimson Pearl and
Verona. I know you can get Petite Pearl vines from
Bevins Creek Nursery in Minnesota. They may have the other varieties as well. Also check out
Northeastern Vine Supply for cold hardy hybrids.